Panadol Cold and Flu Day Caplets is used for the short-term relief of the symptoms colds and flu including fever, headache, body ache, blocked and runny nose. It is a combination of three medicines: Paracetamol, Caffeine and Phenylephrine, which relieves common cold symptoms. Paracetamol is an analgesic (pain reliever) and an anti-pyretic (fever reducer) which works by blocking the release of certain chemical messengers that cause fever and pain. Caffeine increases the effectiveness of paracetamol. Phenylephrine is a decongestant which narrows the small blood vessels providing relief from congestion or stuffiness in the nose. It is a non-drowsy formulation for day time relief.